Product name:Primaquine diphosphate
CAS: 63-45-6
Molecular Formula: C15H27N3O9P2
Molecular Weight: 455.3371
Product description:This product can kill vivax malaria, 3 phase, p. falciparum and p. ovale organization of worm strains, especially for vivax, also can kill various plasmodium gametophyte, function you2 qiang2 of plasmodium falciparum, can't development inside the mosquito, to interrupt transmission. The body of the product inside the red phase is very weak. Primaquine antimalarial mechanism is not entirely clear, may be associated with interference of DNA synthesis, the parasite infrared period insect body with the tissue cells primaquine solution in 8 hours, electron microscope, primaquine can make the malaria parasite mitochondrial morphology change, characterized by swollen mitochondria, and cytoplasm vacuoles appeared. The drug can inhibit the oxidation of the mitochondria, significantly reducing the oxygen uptake of malaria parasites.