Cefpodoxime is sales as the precursor drug Cefpodoxime proxetil to trademark Vantin and to Orelox name; It is the most active against gram-positive and gram-negative organisms most. Function
the product with broad-spectrum third-generation oral cephalosporin, cefpodoxime is a prodrug. The intestinal absorption after oral administration, the intestinal esterase hydrolysis with antibacterial activity of cefpodoxime. Mainly caused by susceptible strains for clinical pneumonia, acute bronchitis, pharyngitis, tonsillitis, pyelonephritis, cystitis, gonococcal urethritis, and skin and soft tissue infections.
cefpodoxime antibacterial effect by inhibiting bacterial cell wall membrane system boundary GGT, the formation of cross-linking of the peptide effect can not be, sticky bacterial cell wall peptide synthesis blocked, resulting in cell wall defects, bacterial cells lose their protective barrier, so that bacteria swelling, deformation, rupture and death. Cefpodoxime of β-lactamases have good stability, and thus many ampicillin-resistant strains or resistant to amoxicillin were effective.
in vitro antimicrobial tests showed that its activity is superior to other β-lactam antibiotics, cefpodoxime show coordination with the host defense agencies bactericidal effect of β-lactamase-producing strains also showed strong antibacterial activity.
Note
the product should be taken after meals.
the adverse reactions were allergic reactions, skin rash, hives, itching, belching and gastrointestinal reactions.
those who are allergic to penicillin with caution. Pseudomembranous colitis was diagnosed in patients with diarrhea, allergy patients, and diuretics in patients with caution.
with other antibiotics, cefpodoxime fat long-term use may lead to non-sensitive micro-organisms (eg Candida, Enterococcus, Clostridium difficult) overgrowth, which may require interruption of treatment.
Read more: Cefpodoxime for sale